Lowes Line
Posted
9/25/26

 




 
Indiana Preview and Prediction
 

By The Lowes Line Staff



Matchup: Northwestern Wildcats (2-0, 0-0) at #5 Indiana Hoosiers (3-0, 0-0)
Date: Friday, September 25, 2026, 7:00 pm CDT, Memorial Stadium
TV: Fox
Line: Indiana (-20.5); O/U 49.5
Outlook:

Last week's Line was a tad bit off, but in the best possible way.  Northwestern entered Northwestern Medicine Library...umm...I mean Field as mere 3.5 point favorites.  After 60 minutes of dominant football against Coach Prime's Colorado Buffaloes, the Purple emerged victorious via a 41-7 drubbing. 

Beyond the scoreboard, the Wildcats thoroughly beat Colorado in every meaningful statistical comparison.  They outgained Colorado by 80 yards, won the turnover battle 4-1, had more first downs, and held the ball on offense for 13 more minutes.  Quarterback Aidan Chiles had a supremely efficient game, going 17 for 22 and 3 touchdown passes.  In addition to the two he ran in himself.  NU continued their running back by committee arrangement and it proved pretty effective against the Buffaloes defense.  The NU coaching staff obviously saw something in the film because Chiles's 3 touchdown passes went to Joseph Himon II.  Himon has developed into a receiving threat out of the backfield. 

The NU defense kept Colorado pretty well bottled up all game, allowing only one touchdown drive to open the second half.  I'm sure many in the Purple fanbase were nervous at that point, since we've seen so many collapses in the past.  But NU responded and scored the next 20 points, turning a game that had the potential to go all white knuckle into a laugher.  A fitting way to end NU's sojourn on the Lakefill.

Northwestern next drives down I-65 to face defending national champions and current 5th-ranked Indiana Hoosiers.  Gone from last year's top-ranked team is 1st overall draft pick Fernando Mendoza.  Coach Cignetti remains, however, and has kept IU playing hard and playing well.  This will be IU's 4th straight home game, and they haven't surrendered a point during the last 2 games, pitching shutouts against Howard and Western Kentucky.  Now, truth be told, neither of those teams (or IU's week 1 opponent, North Texas) are even minimal competition, but still, pitching back-to-back shutouts is still an impressive feat.

Now that Mendoza is plying his trade in the NFL (or what passes for it in Las Vegas), the Hoosiers have turned to Josh Howard to lead the offense.  Through 3 games, albeit against inferior defenses, Hoover has completed 72.5% of his passes and has 10 touchdowns against no interceptions.  Hoover is supported by the aptly named Turbo Richard, who sports a gaudy 7.7-yard rushing average and has crossed the goal line 4 times.  IU is well coached and doesn't give the ball up, so a repeat of the success in taking the ball away against the Buffaloes is unlikely to repeat itself. 

I'd love to say that NU will go into Bloomington and shock the world, but I just don't see that happening.  IU is just too well coached and has playmakers that take care of the ball and make good plays.  The IU defense is on an impressive shutout streak, but I don't see that reaching 180 minutes.  NU entered the week as 23.5 'dogs and that has shrunk a bit to the current 20.5, but I think that makes an IU cover that much more likely.  And, unfortunately, IU plays Rutgers the following week, so NU can't even sneak up on the Hoosiers in trap game fashion.

Pick: Indiana 38, Northwestern 17.  Northwestern likely keeps this game close for a while, but IU's playmakers and discipline are just too much and NU gives up a late score to lose the cover.
Season to date: 2-0 straight up, 0-2 against the spread. 

Go ‘Cats





The
Lowes Line is an e-mailed description of NU's next football game, with an invariably fearless prediction of the outcome and how NU will fare against what the other "experts" predict.  Our good friend and Brother Marcus Lowes began the broadcast mailing in 1996.  The crack Lowes Line Staff (alumni Lone Star Cat, GallopingGrapes, P.S. O'Briant, Eric Cockerill, Joel Kanvik, Charlie Simon, and MO'Cats) have continued the Line in memory of Marcus.  For the 2026 season it has returned to HailToPurple.com, for anyone to enjoy.  Thanks to the gridiron brain trust at the Lowes Line!